For instance, cells of the pancreas that produce the protein insulin, have abundant rough endoplasmic reticulum. What types of cells in a human body contain large amounts of rough ER?Ĭells that specialize in protein secretion contain large amounts of rough endoplasmic reticulum. RER APPEAR ROUGH DUE TO THE PRESENCE OF RIBOSOMES ON ITS SURFACE. The RER prepares proteins because of these ribosomes which is known as the protein synthesis. The RER is rough as it has ribosomes in its structure. The RER appears rough because of the presence ribosomes which manufactures proteins. The cisternae are made up of flattened membrane disks, which are involved in the modification of proteins. It is made up of cisternae, tubules and vesicles. Its main function is to produce proteins. Rough endoplasmic reticulum is an organelle found in eukaryotic cells. So the endoplasmic reticulum is an organelle that’s really a workhorse in producing proteins and substances needed by the rest of the cell. And that smooth endoplasmic reticulum produces other substances needed by the cell. Then there’s the smooth endoplasmic reticulum, which doesn’t have those ribosomes on it. The smooth endoplasmic reticulum (SER) is distinguished from the rough endoplasmic reticulum (RER), the other basic type of endoplasmic reticulum, by its lack of ribosomes, which are protein-synthesizing particles that can be found attached to the outer surface of the RER to give the membrane its “rough” appearance. The organelles would not stay suspended in the solution of a cell without the support of cytoplasm. If a cell would be without cytoplasm it could not retain its shape and would be deflated and flat. A real life example of the Rough Endoplasmic Reticulum would be traffic on a highway. Thee proteins on the ribosomes collect in the Endoplasmic Reticulum to help transport the proteins throughout the cell. What is the rough endoplasmic reticulum like in real life? Protein Folding in the Rough ER Misfolded proteins may not function properly, and this malfunction can even cause human disease. This happens in part because the lipids are too hydrophobic to dissolve into the cytoplasm. This organelle contains the enzymes involved in lipid synthesis, and as lipids are manufactured in the ER, they are inserted into the organelle’s own membranes. Membranes and their constituent proteins are assembled in the ER. How do the ER and cell membrane work together? In addition, it is involved in carbohydrate metabolism. In addition it is important for the synthesis and secretion of steroid hormones from cholesterol and other lipid precursors. The smooth ER is important in the synthesis of lipids, such as cholesterol and phospholipids, which form all the membranes of the organism. Rough ER lies immediately adjacent to the cell nucleus, and its membrane is continuous with the outer membrane of the nuclear envelope. Rough ER is named for its rough appearance, which is due to the ribosomes attached to its outer (cytoplasmic) surface. Whereas, the Rough Endoplasmic Reticulum is bounded by the ribosomes and also stores proteins. The main difference between these two terminologies is that the Smooth Endoplasmic Reticulum is known for stocking the lipids and proteins. What’s the difference between rough ER and smooth ER? Rough ER is called rough because it has ribosomes attached to its surface. Rough ER looks like sheets or disks of bumpy membranes while smooth ER looks more like tubes. Both rough ER and smooth ER have the same types of membranes but they have different shapes. What are the similarities between rough and smooth ER? It is associated with lipid synthesis, carbohydrate metabolism, calcium concentration, drug detoxification, and attachment of receptors on cell membrane proteins. Smooth endoplasmic reticulum (biology definition): (A part of) endoplasmic reticulum that is tubular and lacks ribosomes. Smooth ER is largely associated with lipid (fat) manufacture and metabolism and steroid production hormone production. The rough ER, studded with millions of membrane bound ribosomes, is involved with the production, folding, quality control and despatch of some proteins. What does the smooth and rough ER do in a cell? What are the four major functions of the endoplasmic reticulum?.What types of cells in a human body contain large amounts of rough ER?.What happens if cytoplasm is defective?.What is the rough endoplasmic reticulum like in real life?.How do the ER and cell membrane work together?.
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What membrane is connected to rough ER?.What’s the difference between rough ER and smooth ER?.
![smooth er smooth er](http://3dbiology.pbworks.com/f/smooth_rough_ER.jpg)